By Tony K.L. Kiang,Kyle John Wilby,Mary H.H. Ensom
This entire overview offers a scientific, independent research, critique and precis of the on hand literature and generates novel scientific decision-making algorithms that could reduction clinicians and scientists in perform administration and learn improvement. capability mechanisms for the pointed out drug interactions are deduced from to be had preclinical and in vitro facts that are interpreted within the context of the in vivo findings. present obstacles and gaps within the literature are summarized, and strength destiny study instructions / experimentations also are suggested. as well as the most aim to check the to be had scientific pharmacokinetic and pharmacodynamic drug interactions linked to WHO-recommended antimalarial medications out there at the present time (i.e. chloroquine, amodiaquine, sulfadoxine, pyrimethamine, mefloquine, artemisinin, artemether, artesunate, dihydroartemisinin, artemotil, lumefantrine, primaquine, atovaquone, proguanil, piperaquine and quinine), this e-book additionally presents succinct bankruptcy summaries at the epidemiology of malaria an infection, analysis and therapeutics, in vivo pharmacology and chemistry, preclinical pharmacology, in vitro pharmacodynamics, in vitro response phenotyping, and in vitro drug-drug interplay information linked to the pointed out antimalarial medicines.
Read or Download Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials PDF
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Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials by Tony K.L. Kiang,Kyle John Wilby,Mary H.H. Ensom